| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM50230372 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1644840 (CHEMBL3993769) |
|---|
| IC50 | 118±n/a nM |
|---|
| Citation |  Iyer, MR; Cinar, R; Katz, A; Gao, M; Erdelyi, K; Jourdan, T; Coffey, NJ; Pacher, P; Kunos, G Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB J Med Chem60:1126-1141 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52842.52 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | P47746 |
|---|
| Residue: | 473 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM50230372 |
|---|
| n/a |
|---|
| Name | BDBM50230372 |
|---|
| Synonyms: | CHEMBL4080203 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H24ClN5O2S |
|---|
| Mol. Mass. | 530.04 |
|---|
| SMILES | C\C(N)=N/C(=N\S(=O)(=O)c1ccc2ccccc2c1)/N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1 |c:24| |
|---|
| Structure | 
|
|---|
Search and Browse
