| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
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| Ligand | BDBM50230969 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1645058 (CHEMBL3993987) |
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| Ki | 0.500000±n/a nM |
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| Citation |  Landagaray, E; Ettaoussi, M; Rami, M; Boutin, JA; Caignard, DH; Delagrange, P; Melnyk, P; Berthelot, P; Yous, S New quinolinic derivatives as melatonergic ligands: Synthesis and pharmacological evaluation. Eur J Med Chem127:621-631 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1B |
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| Name: | Melatonin receptor type 1B |
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| Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 40203.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49286 |
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| Residue: | 362 |
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| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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| BDBM50230969 |
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| n/a |
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| Name | BDBM50230969 |
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| Synonyms: | CHEMBL4070527 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H18N2O2 |
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| Mol. Mass. | 270.3263 |
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| SMILES | COc1ccc2cccc(CCC(=O)NC3CC3)c2n1 |
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| Structure | 
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