| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50231594 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1645470 (CHEMBL3994399) |
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| Ki | 650±n/a nM |
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| Citation |  Koul, S; Ramdas, V; Barawkar, DA; Waman, YB; Prasad, N; Madadi, SK; Shejul, YD; Bonagiri, R; Basu, S; Menon, S; Reddy, SB; Chaturvedi, S; Chennamaneni, SR; Bedse, G; Thakare, R; Gundu, J; Chaudhary, S; De, S; Meru, AV; Palle, V; Chugh, A; Mookhtiar, KA Design and synthesis of novel, potent and selective hypoxanthine analogs as adenosine A Bioorg Med Chem25:1963-1975 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50231594 |
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| n/a |
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| Name | BDBM50231594 |
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| Synonyms: | CHEMBL4065762 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N4O2 |
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| Mol. Mass. | 352.4302 |
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| SMILES | CCCn1c(nc2nc([nH]c2c1=O)C1CCCC1)-c1cccc(OC)c1 |
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| Structure | 
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