| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50232944 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1649599 (CHEMBL3998733) |
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| Ki | 240±n/a nM |
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| Citation |  Ragusa, G; Gómez-Cañas, M; Morales, P; Rodríguez-Cueto, C; Pazos, MR; Asproni, B; Cichero, E; Fossa, P; Pinna, GA; Jagerovic, N; Fernández-Ruiz, J; Murineddu, G New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking. Eur J Med Chem127:398-412 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50232944 |
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| n/a |
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| Name | BDBM50232944 |
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| Synonyms: | CHEMBL4094331 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28ClN3O2 |
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| Mol. Mass. | 449.972 |
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| SMILES | Cc1ccc(Cn2nc(cc(C(=O)NC3CCCCC3)c2=O)-c2ccc(Cl)c(C)c2)cc1 |
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| Structure | 
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