| Reaction Details |
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 | Report a problem with these data |
| Target | Steroid hormone receptor ERR2 |
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| Ligand | BDBM50233267 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1650379 (CHEMBL3999513) |
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| IC50 | 350±n/a nM |
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| Citation |  Yu, DD; Huss, JM; Li, H; Forman, BM Identification of novel inverse agonists of estrogen-related receptors ERR¿ and ERRß. Bioorg Med Chem25:1585-1599 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Steroid hormone receptor ERR2 |
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| Name: | Steroid hormone receptor ERR2 |
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| Synonyms: | ERR beta-2 | ERR-beta | ERR2_HUMAN | ERRB2 | ESRL2 | ESRRB | Estrogen receptor-like 2 | Estrogen-related receptor beta | NR3B2 | Nuclear receptor subfamily 3 group B member 2 | Steroid hormone receptor ERR2 | Steroid hormone receptor ERR2 Beta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48061.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_11254 |
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| Residue: | 433 |
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| Sequence: | MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP
MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC
EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG
GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL
TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV
YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
MHKLFLEMLEAKV
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| BDBM50233267 |
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| n/a |
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| Name | BDBM50233267 |
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| Synonyms: | CHEMBL4084142 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H31NO4 |
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| Mol. Mass. | 445.55 |
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| SMILES | COC(=O)CC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 |
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| Structure | 
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