| Reaction Details |
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 | Report a problem with these data |
| Target | Estrogen-related receptor gamma |
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| Ligand | BDBM50233273 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1650380 (CHEMBL3999514) |
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| IC50 | 350±n/a nM |
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| Citation |  Yu, DD; Huss, JM; Li, H; Forman, BM Identification of novel inverse agonists of estrogen-related receptors ERR¿ and ERRß. Bioorg Med Chem25:1585-1599 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Estrogen-related receptor gamma |
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| Name: | Estrogen-related receptor gamma |
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| Synonyms: | ERR gamma-2 | ERR3 | ERR3_HUMAN | ERRG2 | ESRRG | Estrogen receptor-related protein 3 | Estrogen-Related Receptor, gamma | Estrogen-related receptor gamma | KIAA0832 | NR3B3 | Nuclear receptor subfamily 3 group B member 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51305.00 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1501351 |
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| Residue: | 458 |
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| Sequence: | MDSVELCLPESFSLHYEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGG
SSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYML
NSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSC
QACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSH
LLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSL
LQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMK
LEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMT
LPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV
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| BDBM50233273 |
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| n/a |
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| Name | BDBM50233273 |
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| Synonyms: | CHEMBL4064664 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H35NO4 |
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| Mol. Mass. | 473.6032 |
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| SMILES | CC(CO)C\C(=C(\c1ccc(OCCN(C)C)cc1)c1ccc(OC(C)=O)cc1)c1ccccc1 |
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| Structure | 
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