| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
|---|
| Ligand | BDBM50233600 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1651007 (CHEMBL4000262) |
|---|
| Ki | 2.1±n/a nM |
|---|
| Citation |  Nikas, SP; Sharma, R; Paronis, CA; Kulkarni, S; Thakur, GA; Hurst, D; Wood, JT; Gifford, RS; Rajarshi, G; Liu, Y; Raghav, JG; Guo, JJ; Järbe, TU; Reggio, PH; Bergman, J; Makriyannis, A Probing the carboxyester side chain in controlled deactivation (-)-d(8)-tetrahydrocannabinols. J Med Chem58:665-81 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 2 |
|---|
| Name: | Cannabinoid receptor 2 |
|---|
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 38220.43 |
|---|
| Organism: | MOUSE |
|---|
| Description: | P47936 |
|---|
| Residue: | 347 |
|---|
| Sequence: | MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILS
SRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLD
VRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYA
LRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
|
|
|
|---|
| BDBM50233600 |
|---|
| n/a |
|---|
| Name | BDBM50233600 |
|---|
| Synonyms: | CHEMBL4098428 | US10882838, Example 1.10 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H34N2O4 |
|---|
| Mol. Mass. | 438.5592 |
|---|
| SMILES | [H][C@@]12CC(C)=CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)C(C)(C)C(=O)OCCCn1ccnc1 |r,c:4| |
|---|
| Structure | 
|
|---|
Search and Browse
