| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50233625 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1651022 (CHEMBL4000277) |
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| Ki | 18±n/a nM |
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| Citation |  Szabo, M; Lim, HD; Herenbrink, CK; Christopoulos, A; Lane, JR; Capuano, B Proof of concept study for designed multiple ligands targeting the dopamine D2, serotonin 5-HT2A, and muscarinic M1 acetylcholine receptors. J Med Chem58:1550-5 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50233625 |
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| n/a |
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| Name | BDBM50233625 |
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| Synonyms: | CHEMBL4090568 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N4O2S |
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| Mol. Mass. | 408.517 |
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| SMILES | O=C1COc2ccccc2N1CCCN1CCN(CC1)c1nsc2ccccc12 |
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| Structure | 
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