| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50233625 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1651027 |
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| Ki | 5.8±n/a nM |
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| Citation |  Szabo M; Lim HD; Herenbrink CK; Christopoulos A; Lane JR; Capuano B Proof of concept study for designed multiple ligands targeting the dopamine D2, serotonin 5-HT2A, and muscarinic M1 acetylcholine receptors. J Med Chem 58:1550-5 (2015) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | Dopamine D2 receptor and serotonin 2a receptor |
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| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | HTR2 | HTR2A | Serotonin receptor 2A |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52607.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 471 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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| BDBM50233625 |
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| n/a |
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| Name | BDBM50233625 |
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| Synonyms: | CHEMBL4090568 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N4O2S |
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| Mol. Mass. | 408.517 |
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| SMILES | O=C1COc2ccccc2N1CCCN1CCN(CC1)c1nsc2ccccc12 |
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| Structure | 
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