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TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1
LigandBDBM50234003
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1651957 (CHEMBL4001212)
IC50 4290±n/a nM
Citation Li, KLi, LWang, SLi, XMa, TLiu, DJing, YZhao, L Design and synthesis of novel 2-substituted 11-keto-boswellic acid heterocyclic derivatives as anti-prostate cancer agents with Pin1 inhibition ability. Eur J Med Chem126:910-919 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Name:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Synonyms:PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Type:PROTEIN
Mol. Mass.:18248.11
Organism:Homo sapiens (Human)
Description:ChEMBL_1502595
Residue:163
Sequence:
MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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  Blast E-value cutoff:
BDBM50234003
n/a
NameBDBM50234003
Synonyms:CHEMBL4085308
TypeSmall organic molecule
Emp. Form.C34H49IN2O3
Mol. Mass.660.6689
SMILES[H][C@@]12CC[C@]3(C)[C@]([H])(C(=O)C=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@]5(C)CC[C@@]34C)[C@@]1(C)C=C(I)C(=O)[C@]2(C)C(=O)N1CCNCC1 |r,t:10,32|
Structure
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