| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
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| Ligand | BDBM18073 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1653677 (CHEMBL4003043) |
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| IC50 | 80210±n/a nM |
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| Citation |  Miliutina, M; Ejaz, SA; Khan, SU; Iaroshenko, VO; Villinger, A; Iqbal, J; Langer, P Synthesis, alkaline phosphatase inhibition studies and molecular docking of novel derivatives of 4-quinolones. Eur J Med Chem126:408-420 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Intestinal-type alkaline phosphatase |
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| Name: | Intestinal-type alkaline phosphatase |
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| Synonyms: | ALPI | Intestinal alkaline phosphatase | Intestinal alkaline phosphatase (IAP) | Intestinal-type alkaline phosphatase (IAP) | PPBI_BOVIN |
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| Type: | Protein |
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| Mol. Mass.: | 57094.82 |
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| Organism: | Bos taurus (Cattle) |
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| Description: | P19111 |
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| Residue: | 533 |
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| Sequence: | MQGACVLLLLGLHLQLSLGLVPVEEEDPAFWNRQAAQALDVAKKLQPIQTAAKNVILFLG
DGMGVPTVTATRILKGQMNGKLGPETPLAMDQFPYVALSKTYNVDRQVPDSAGTATAYLC
GVKGNYRTIGVSAAARYNQCKTTRGNEVTSVMNRAKKAGKSVGVVTTTRVQHASPAGAYA
HTVNRNWYSDADLPADAQMNGCQDIAAQLVNNMDIDVILGGGRKYMFPVGTPDPEYPDDA
SVNGVRKRKQNLVQAWQAKHQGAQYVWNRTALLQAADDSSVTHLMGLFEPADMKYNVQQD
HTKDPTLQEMTEVALRVVSRNPRGFYLFVEGGRIDHGHHDDKAYMALTEAGMFDNAIAKA
NELTSELDTLILVTADHSHVFSFGGYTLRGTSIFGLAPSKALDSKSYTSILYGNGPGYAL
GGGSRPDVNDSTSEDPSYQQQAAVPQASETHGGEDVAVFARGPQAHLVHGVEEETFVAHI
MAFAGCVEPYTDCNLPAPTTATSIPDAAHLAASPPPLALLAGAMLLLLAPTLY
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| BDBM18073 |
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| n/a |
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| Name | BDBM18073 |
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| Synonyms: | (2S)-2-amino-3-phenylpropanoic acid | CHEMBL301523 | L-[2,3,4,5,6-3H]phenylalanine | L-phenylalanine | Phenylalanine | US11021454, Compound L-phe |
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| Type | Amino Acid |
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| Emp. Form. | C9H11NO2 |
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| Mol. Mass. | 165.1891 |
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| SMILES | N[C@@H](Cc1ccccc1)C(O)=O |
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| Structure | 
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