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TargetCoagulation factor VII/tissue factor
LigandBDBM50235142
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1654816
IC50 0.078000±n/a nM
Citation Wang WWXu SHZhao YZZhang CZhang YYYu BYZhang J Microbial hydroxylation and glycosylation of pentacyclic triterpenes as inhibitors on tissue factor procoagulant activity. Bioorg Med Chem Lett 27:1026-1030 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Coagulation factor VII/tissue factor
Name:Coagulation factor VII/tissue factor
Synonyms:CD_antigen=CD142 | Coagulation factor III | TF | Thromboplastin | Tissue factor
Type:PROTEIN
Mol. Mass.:33067.61
Organism:Homo sapiens (Human)
Description:ChEMBL_936735
Residue:295
Sequence:
METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
PVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGS
AGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFG
KDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVE
CMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50235142
n/a
NameBDBM50235142
Synonyms:CHEMBL4070749
TypeSmall organic molecule
Emp. Form.C36H58O8
Mol. Mass.618.8409
SMILES[H][C@@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(C)=C |r|
Structure
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