| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxylic ester hydrolase |
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| Ligand | BDBM50159614 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1655009 (CHEMBL4004375) |
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| IC50 | 3.2±n/a nM |
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| Citation |  Singh, H; Singh, JV; Gupta, MK; Singh, P; Sharma, S; Nepali, K; Bedi, PMS Benzoflavones as cholesterol esterase inhibitors: Synthesis, biological evaluation and docking studies. Bioorg Med Chem Lett27:850-854 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Carboxylic ester hydrolase |
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| Name: | Carboxylic ester hydrolase |
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| Synonyms: | 3.1.1.- | CEL | Carboxylic ester hydrolase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63554.81 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_117582 |
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| Residue: | 585 |
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| Sequence: | MGSSELVIWCLACCLAAARAAKLGSVYTEGGFVEGVNKKLSLLGDSVDIFKGIPFAAAPK
ALENPQRHPGWQGTLKAKDFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKEVSRDLPV
MIWIYGGAFLMGSGQGANFLSNYLYDGEELATRGNVIVVTFNYRVGPLGFLSTGDANLPG
NYGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGGASVSLQTLSPYNKGLIKRAISQS
GVALSPWAIQKNPLSWAKTIAEKVGCPMDDTARMARCLKITDPRALTLAYKLPLTKQEFP
VVHYLGFIPVVDGDFIPDDPVNLYANAADIDYLAGTNDMDGHLFATVDLPAVDKDKKTIT
EEDFYKLVSGFTIVKGPRGANITFDVYTASWAQDSSQETKKKTVVDLETDILFLMPTETA
VAQHRANAKSAQTYTYVFAHPSRMPVYPSWYVFGKPFAMIAYWTNFARSGDPNMGGSSVP
THWEPYTLESSKYLEITNKMDSSSMKQDLRTSYLQYWATTYQALPTVADEGAIPVPPTGD
SEATPAPPTGDPEATPAPPTGDSEATPAPPPSDAEVAQMPIVIGF
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| BDBM50159614 |
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| n/a |
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| Name | BDBM50159614 |
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| Synonyms: | 2-(2-Fluoro-phenyl)-benzo[h]chromen-4-one | CHEMBL361608 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H11FO2 |
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| Mol. Mass. | 290.2878 |
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| SMILES | Fc1ccccc1-c1cc(=O)c2ccc3ccccc3c2o1 |
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| Structure | 
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