| Reaction Details |
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 | Report a problem with these data |
| Target | Retinal dehydrogenase 2 |
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| Ligand | BDBM50409029 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1659727 (CHEMBL4009339) |
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| IC50 | 4500±n/a nM |
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| Citation |  Buchman, CD; Hurley, TD Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives. J Med Chem60:2439-2455 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinal dehydrogenase 2 |
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| Name: | Retinal dehydrogenase 2 |
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| Synonyms: | AL1A2_HUMAN | ALDH1A2 | Aldehyde dehydrogenase family 1 member A2 | RALDH 2 | RALDH(II) | RALDH2 | Retinal dehydrogenase 2 | Retinaldehyde-specific dehydrogenase type 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56720.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109700 |
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| Residue: | 518 |
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| Sequence: | MTSSKIEMPGEVKADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNP
ATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVL
ATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVC
GQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILP
GYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADAD
LDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQG
PQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFG
PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQ
SPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS
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| BDBM50409029 |
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| n/a |
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| Name | BDBM50409029 |
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| Synonyms: | DAIDZIN |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20O9 |
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| Mol. Mass. | 416.3781 |
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| SMILES | OC[C@H]1O[C@@H](Oc2ccc3c(c2)occ(-c2ccc(O)cc2)c3=O)[C@H](O)[C@@H](O)[C@@H]1O |r| |
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| Structure | 
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