| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 5A, mitochondrial |
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| Ligand | BDBM50237367 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1660853 (CHEMBL4010465) |
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| Ki | 32±n/a nM |
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| Citation |  Carta, F; Birkmann, A; Pfaff, T; Buschmann, H; Schwab, W; Zimmermann, H; Maresca, A; Supuran, CT Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action. J Med Chem60:3154-3164 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 5A, mitochondrial |
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| Name: | Carbonic anhydrase 5A, mitochondrial |
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| Synonyms: | CA-VA | CA5 | CA5A | CAH5A_HUMAN | Carbonate dehydratase VA | Carbonic Anhydrase VA | Carbonic anhydrase 5A (CA VA) | Carbonic anhydrase 5A, mitochondrial | Carbonic anhydrase 5A, mitochondrial precursor | Carbonic anhydrase V | Carbonic anhydrase VA (CA VA) |
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| Type: | Enzyme |
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| Mol. Mass.: | 34755.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human (cloned) isozyme |
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| Residue: | 305 |
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| Sequence: | MLGRNTWKTSAFSFLVEQMWAPLWSRSMRPGRWCSQRSCAWQTSNNTLHPLWTVPVSVPG
GTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATEASGISGGPL
ENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVI
GVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCWDYWTYAGSLTTPPLT
ESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVWASFQATN
EGTRS
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| BDBM50237367 |
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| n/a |
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| Name | BDBM50237367 |
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| Synonyms: | CHEMBL4090091 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17N5O3S2 |
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| Mol. Mass. | 391.468 |
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| SMILES | CN(C(=O)Cc1ccc(cc1)-n1cccn1)c1nc(C)c(s1)S(N)(=O)=O |
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| Structure | 
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