| Reaction Details |
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 | Report a problem with these data |
| Target | Transmembrane domain-containing protein TMIGD3 |
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| Ligand | BDBM50236775 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1661723 (CHEMBL4011335) |
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| Ki | 770±n/a nM |
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| Citation |  Tosh, DK; Janowsky, A; Eshleman, AJ; Warnick, E; Gao, ZG; Chen, Z; Gizewski, E; Auchampach, JA; Salvemini, D; Jacobson, KA Scaffold Repurposing of Nucleosides (Adenosine Receptor Agonists): Enhanced Activity at the Human Dopamine and Norepinephrine Sodium Symporters. J Med Chem60:3109-3123 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transmembrane domain-containing protein TMIGD3 |
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| Name: | Transmembrane domain-containing protein TMIGD3 |
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| Synonyms: | TMIG3_HUMAN | TMIGD3 | Transmembrane domain-containing protein TMIGD3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30335.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_114868 |
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| Residue: | 266 |
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| Sequence: | MEGSPAGPIEQKEARWESSWEEQPDWTLGCLSPESQFRIPGLPGCILSFQLKVCFLPVMW
LFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYKNHPKYWCRGYFRDYCNIIAF
SPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRDFARDDMDFTELIVTDDKGTLA
NDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQR
NRRVGNTLKPFSRVLTPKEMAPTEQM
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| BDBM50236775 |
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| n/a |
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| Name | BDBM50236775 |
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| Synonyms: | CHEMBL4105446 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H30ClN5O4S |
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| Mol. Mass. | 556.076 |
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| SMILES | [H][C@]12C[C@]1([C@@H](O)[C@@H](O)[C@@H]2n1cnc2c(NC)nc(nc12)C#Cc1ccc(Cl)s1)C(=O)OCCC1CCCCC1 |r| |
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| Structure | 
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