| Reaction Details |
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 | Report a problem with these data |
| Target | Lactoperoxidase |
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| Ligand | BDBM50238832 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1664243 (CHEMBL4013924) |
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| IC50 | 3900±n/a nM |
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| Citation |  Soubhye, J; Chikh Alard, I; Aldib, I; Prévost, M; Gelbcke, M; De Carvalho, A; Furtmüller, PG; Obinger, C; Flemmig, J; Tadrent, S; Meyer, F; Rousseau, A; Nève, J; Mathieu, V; Zouaoui Boudjeltia, K; Dufrasne, F; Van Antwerpen, P Discovery of Novel Potent Reversible and Irreversible Myeloperoxidase Inhibitors Using Virtual Screening Procedure. J Med Chem60:6563-6586 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lactoperoxidase |
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| Name: | Lactoperoxidase |
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| Synonyms: | LPO | Lactoperoxidase (LPO) | PERL_BOVIN |
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| Type: | Enzyme |
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| Mol. Mass.: | 80659.97 |
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| Organism: | Bos taurus (Bovine) |
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| Description: | P80025 |
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| Residue: | 712 |
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| Sequence: | MWVCLQLPVFLASVTLFEVAASDTIAQAASTTTISDAVSKVKIQVNKAFLDSRTRLKTTL
SSEAPTTQQLSEYFKHAKGRTRTAIRNGQVWEESLKRLRRDTTLTNVTDPSLDLTALSWE
VGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQ
RKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNE
HSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAV
TSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTT
ARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAF
IQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDE
NYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQ
PTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDL
YKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDS
LQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN
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| BDBM50238832 |
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| n/a |
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| Name | BDBM50238832 |
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| Synonyms: | CHEMBL4080413 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H10FN5 |
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| Mol. Mass. | 219.2183 |
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| SMILES | [#6]-c1nc(\[#7]=[#6](/[#7])-[#7])nc2cc(F)ccc12 |
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| Structure | 
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