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TargetDeath-associated protein kinase 2
LigandBDBM50024284
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1664713 (CHEMBL4014509)
IC50 55000±n/a nM
Citation Wang, SXu, LLu, YTLiu, YFHan, BLiu, TTang, JLi, JWu, JLi, JYYu, LFYang, F Discovery of benzofuran-3(2H)-one derivatives as novel DRAK2 inhibitors that protect islet?-cells from apoptosis. Eur J Med Chem130:195-208 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Death-associated protein kinase 2
Name:Death-associated protein kinase 2
Synonyms:DAP kinase 2 | DAP-kinase-related protein 1 | DAPK2 | DAPK2_HUMAN | DRP-1
Type:PROTEIN
Mol. Mass.:42900.09
Organism:Homo sapiens (Human)
Description:ChEMBL_774557
Residue:370
Sequence:
MFQASMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSR
ASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKES
LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIED
GVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANIT
AVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESV
VNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRKA
LHPRRRSSTS
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  Blast E-value cutoff:
BDBM50024284
n/a
NameBDBM50024284
Synonyms:CHEMBL3334979
TypeSmall organic molecule
Emp. Form.C22H24N2O3S
Mol. Mass.396.503
SMILESCOc1ccc(cc1OC)-c1cnc2scc(NC(=O)C3CCCCC3)c2c1
Structure
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