Reaction Details |
| Report a problem with these data |
Target | 5-hydroxytryptamine receptor 5B |
---|
Ligand | BDBM50005835 |
---|
Substrate/Competitor | n/a |
---|
Ki | 7943.28±n/a nM |
---|
Comments | PDSP_1788 |
---|
Citation | Matthes, H; Boschert, U; Amlaiky, N; Grailhe, R; Plassat, JL; Muscatelli, F; Mattei, MG; Hen, R Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. Mol Pharmacol43:313-9 (1993) [PubMed] |
---|
More Info.: | Get all data from this article |
---|
|
5-hydroxytryptamine receptor 5B |
---|
Name: | 5-hydroxytryptamine receptor 5B |
Synonyms: | 5-HT5B | 5-hydroxytryptamine receptor 5B | 5HT5B_MOUSE | 5ht5b | Htr5b |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 41221.13 |
Organism: | MOUSE |
Description: | 5-HT5B 0 MOUSE::P31387 |
Residue: | 370 |
Sequence: | MEVSNLSGATPGLAFPPGPESCSDSPSSGRSMGSTPGGLILPGREPPFSAFTVLVVTLLV
LLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAVLVMPLSLVSELSAGRRW
QLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRSRASALMIAITWA
LSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYLPLAVVLFVYWKIYKAA
KFRFGRRRRAVVPLPATTQAKEAPPESEMVFTARRRATVTFQTSGDSWREQKEKRAAMMV
GILIGVFVLCWIPFFLTELISPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNN
AFKSLFTKQR
|
|
|
BDBM50005835 |
---|
n/a |
---|
Name | BDBM50005835 |
Synonyms: | (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide | 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide | 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide | 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide | 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide | CHEMBL128 | SUMATRIPTAN | Sumatran | Sumax |
Type | Small organic molecule |
Emp. Form. | C14H21N3O2S |
Mol. Mass. | 295.4 |
SMILES | CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 |
Structure |
|