| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM84939 |
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| Substrate/Competitor | n/a |
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| Ki | 56.8±n/a nM |
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| Comments | PDSP_1130 |
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| Citation |  Nelson, DL; Lucaites, VL; Audia, JE; Nissen, JS; Wainscott, DB Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines. J Pharmacol Exp Ther265:1272-9 (1993) [PubMed] |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT2 | 5HT2A_MACMU | HTR2A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52607.65 |
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| Organism: | Monkey |
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| Description: | 5-HT2 0 Monkey::P50128 |
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| Residue: | 471 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLNEDTRLYSNDFNSGEANTSDAFNWTVESENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
RDPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEDASKDNSDGVNEKVSCV
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| BDBM84939 |
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| n/a |
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| Name | BDBM84939 |
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| Synonyms: | 1,6-Dimethylergoline-8β-carboxylic acid 2-hydroxy-1-methylpropyl ester | LY 108742 | LY-108742 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H28N2O3 |
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| Mol. Mass. | 356.4586 |
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| SMILES | CC(O)C(C)OC(=O)[C@@H]1C[C@H]2[C@@H](Cc3cn(C)c4cccc2c34)N(C)C1 |
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| Structure | 
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