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Target5-hydroxytryptamine receptor 2A
LigandBDBM84933
Substrate/Competitorn/a
Ki 3.6±n/a nM
CommentsPDSP_1132
Citation Nelson, DLLucaites, VLAudia, JENissen, JSWainscott, DB Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines. J Pharmacol Exp Ther265:1272-9 (1993) [PubMed]
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5-hydroxytryptamine receptor 2A
Name:5-hydroxytryptamine receptor 2A
Synonyms:5-HT-2 | 5-HT-2A | 5-HT2 | 5-HT2A | 5HT2A_PIG | HTR2A | Serotonin 2a (5-HT2a) receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:52679.13
Organism:PIG
Description:5-HT2 0 0::P50129
Residue:470
Sequence:
MDVLCEENTSLSSPTNSFMQLNDDTRLYHNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHRRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGAL
LNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKS
SQLQTGQKENSKQDDKATENDCTMVALGKQHSEDAPADNSNTVNEKVSCV
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  Blast E-value cutoff:
BDBM84933
n/a
NameBDBM84933
Synonyms:6-Methyl-N-cyclohexylergoline-8-beta-carboxamide | LY 193525 | LY-193525
TypeSmall organic molecule
Emp. Form.C22H29N3O
Mol. Mass.351.4852
SMILESCN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)NC1CCCCC1
Structure
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