Reaction Details |
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Target | 5-hydroxytryptamine receptor 6 |
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Ligand | BDBM22870 |
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Substrate/Competitor | n/a |
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Ki | 50±n/a nM |
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Comments | PDSP_290 |
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Citation | Kohen, R; Metcalf, MA; Khan, N; Druck, T; Huebner, K; Lachowicz, JE; Meltzer, HY; Sibley, DR; Roth, BL; Hamblin, MW Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. J Neurochem66:47-56 (1996) [PubMed] Article |
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More Info.: | Get all data from this article |
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5-hydroxytryptamine receptor 6 |
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Name: | 5-hydroxytryptamine receptor 6 |
Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 46968.43 |
Organism: | Homo sapiens (Human) |
Description: | P50406 |
Residue: | 440 |
Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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BDBM22870 |
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n/a |
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Name | BDBM22870 |
Synonyms: | 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene | 2-chloro-11-piperazin-1-yldibenzo[b,f][1,4]oxazepine | Amoxapine | Asendin | CHEMBL1113 | Demolox |
Type | Small organic molecule |
Emp. Form. | C17H16ClN3O |
Mol. Mass. | 313.781 |
SMILES | Clc1ccc2Oc3ccccc3N=C(N3CCNCC3)c2c1 |t:13| |
Structure |
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