| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
|---|
| Ligand | BDBM35256 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 55±n/a nM |
|---|
| Comments | PDSP_1235 |
|---|
| Citation |  Kohen, R; Metcalf, MA; Khan, N; Druck, T; Huebner, K; Lachowicz, JE; Meltzer, HY; Sibley, DR; Roth, BL; Hamblin, MW Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. J Neurochem66:47-56 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| 5-hydroxytryptamine receptor 6 |
|---|
| Name: | 5-hydroxytryptamine receptor 6 |
|---|
| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 46968.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P50406 |
|---|
| Residue: | 440 |
|---|
| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
|
|
|
|---|
| BDBM35256 |
|---|
| n/a |
|---|
| Name | BDBM35256 |
|---|
| Synonyms: | (S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+) | MIANSERIN (-) | Tolvon |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H20N2 |
|---|
| Mol. Mass. | 264.3648 |
|---|
| SMILES | [H][C@]12CN(C)CCN1c1ccccc1Cc1ccccc21 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
