Reaction Details |
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Target | 5-hydroxytryptamine receptor 6 |
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Ligand | BDBM81498 |
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Substrate/Competitor | n/a |
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Ki | 570±n/a nM |
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Comments | PDSP_1643 |
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Citation | Kohen, R; Metcalf, MA; Khan, N; Druck, T; Huebner, K; Lachowicz, JE; Meltzer, HY; Sibley, DR; Roth, BL; Hamblin, MW Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. J Neurochem66:47-56 (1996) [PubMed] Article |
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More Info.: | Get all data from this article |
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5-hydroxytryptamine receptor 6 |
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Name: | 5-hydroxytryptamine receptor 6 |
Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 46968.43 |
Organism: | Homo sapiens (Human) |
Description: | P50406 |
Residue: | 440 |
Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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BDBM81498 |
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n/a |
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Name | BDBM81498 |
Synonyms: | 5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole(RU-24969) | CAS_108028 | CHEMBL18785 | NSC_108028 | RU 24969 |
Type | Small organic molecule |
Emp. Form. | C14H16N2O |
Mol. Mass. | 228.2896 |
SMILES | COc1ccc2[nH]cc(C3=CCNCC3)c2c1 |t:9| |
Structure |
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