| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM81770 |
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| Substrate/Competitor | n/a |
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| Ki | 721±n/a nM |
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| Comments | PDSP_1797 |
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| Citation |  Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs. Psychopharmacology (Berl)120:365-8 (1995) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41307.65 |
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| Organism: | RAT |
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| Description: | DOPAMINE D4.4 0 RAT::P30729 |
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| Residue: | 387 |
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| Sequence: | MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASER
ILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASI
FNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVC
CLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPV
SDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRK
RGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVN
SALNPIIYTIFNAEFRSVFRKTLRLRC
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| BDBM81770 |
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| n/a |
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| Name | BDBM81770 |
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| Synonyms: | CAS_82650-83-7 | NSC_3086153 | TENILAPINE |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16N4S2 |
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| Mol. Mass. | 340.466 |
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| SMILES | CN1CCN(CC1)C1=Nc2cscc2C(=CC#N)c2cscc12 |w:15.17,t:8| |
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| Structure | 
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