| Reaction Details |
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 | Report a problem with these data |
| Target | Glycine amidinotransferase, mitochondrial |
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| Ligand | BDBM22913 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_2292 |
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| Citation |  Leurs, R; Tulp, MT; Menge, WM; Adolfs, MJ; Zuiderveld, OP; Timmerman, H Evaluation of the receptor selectivity of the H3 receptor antagonists, iodophenpropit and thioperamide: an interaction with the 5-HT3 receptor revealed. Br J Pharmacol116:2315-21 (1995) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Glycine amidinotransferase, mitochondrial |
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| Name: | Glycine amidinotransferase, mitochondrial |
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| Synonyms: | Agat | GATM_RAT | Gatm | Glycine | Glycine amidinotransferase, mitochondrial |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48247.66 |
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| Organism: | RAT |
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| Description: | Glycine 0 RAT::P50442 |
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| Residue: | 423 |
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| Sequence: | MLRVRCLRGGSRGAEAVHYIGSRLGGSLTGWVQRTFQSTQAATASSQNSCAAEDKATHPL
PKDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQKNGGLYFPKDHL
KKAVAEVEEMCNILSMEGVTVKRPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEII
EAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQDYPIHSVEDRHKLAA
QGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPN
PMHIDATFNIIGPGLVLSNPDRPCHQIDLFKKAGWTIVTPPTPVIPDDHPLWMSSKWLSM
NVLMLDEKRVMVDANEVPIQKMFEKLGISTIKVNIRNANSLGGGFHCWTCDVRRRGTLQS
YFD
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| BDBM22913 |
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| n/a |
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| Name | BDBM22913 |
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| Synonyms: | CHEMBL1237146 | CHEMBL498770 | Iodophenpropit | {[3-(1H-imidazol-5-yl)propyl]sulfanyl}-N''-[2-(4-iodophenyl)ethyl]methanimidamide |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19IN4S |
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| Mol. Mass. | 414.308 |
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| SMILES | NC(SCCCc1cnc[nH]1)=NCCc1ccc(I)cc1 |w:11.12| |
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| Structure | 
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