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TargetProtachykinin-1
LigandBDBM22913
Substrate/Competitorn/a
Ki>10000±n/a nM
CommentsPDSP_2292
Citation Leurs, RTulp, MTMenge, WMAdolfs, MJZuiderveld, OPTimmerman, H Evaluation of the receptor selectivity of the H3 receptor antagonists, iodophenpropit and thioperamide: an interaction with the 5-HT3 receptor revealed. Br J Pharmacol116:2315-21 (1995) [PubMed]  Article
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Protachykinin-1
Name:Protachykinin-1
Synonyms:NKA | NKNA | Protachykinin-1 | Substance P | TAC1 | TAC2 | TKN1_HUMAN
Type:Enzyme Catalytic Domain
Mol. Mass.:15006.99
Organism:Homo sapiens (Human)
Description:Substance P 0 HUMAN::P20366
Residue:129
Sequence:
MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPK
PQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERS
AMQNYERRR
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  Blast E-value cutoff:
BDBM22913
n/a
NameBDBM22913
Synonyms:CHEMBL1237146 | CHEMBL498770 | Iodophenpropit | {[3-(1H-imidazol-5-yl)propyl]sulfanyl}-N''-[2-(4-iodophenyl)ethyl]methanimidamide
TypeSmall organic molecule
Emp. Form.C15H19IN4S
Mol. Mass.414.308
SMILESNC(SCCCc1cnc[nH]1)=NCCc1ccc(I)cc1 |w:11.12|
Structure
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