| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50008782 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 0.12±n/a nM |
|---|
| Comments | PDSP_789 |
|---|
| Citation |  Seeman, P; Van Tol, HH Deriving the therapeutic concentrations for clozapine and haloperidol: the apparent dissociation constant of a neuroleptic at the dopamine D2 or D4 receptor varies with the affinity of the competing radioligand. Eur J Pharmacol291:59-66 (1995) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DRD2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 50730.78 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | F1SM69 |
|---|
| Residue: | 443 |
|---|
| Sequence: | MDPLNLSWYDDDLESRNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHALHSTPDSPARPEKNGHAKDHPKIAKIFEIQSMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
|
|
|
|---|
| BDBM50008782 |
|---|
| n/a |
|---|
| Name | BDBM50008782 |
|---|
| Synonyms: | CHEMBL44237 | EPIDEPRIDE | Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H23IN2O3 |
|---|
| Mol. Mass. | 418.2699 |
|---|
| SMILES | CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC |
|---|
| Structure | 
|
|---|
Search and Browse
