| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM7966 |
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| Substrate/Competitor | n/a |
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| Ki | 17±n/a nM |
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| Comments | PDSP_934 |
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| Citation |  Borsini, F; Giraldo, E; Monferini, E; Antonini, G; Parenti, M; Bietti, G; Donetti, A BIMT 17, a 5-HT2A receptor antagonist and 5-HT1A receptor full agonist in rat cerebral cortex. Naunyn Schmiedebergs Arch Pharmacol352:276-82 (1995) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2_RAT | Hrh2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40269.37 |
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| Organism: | RAT |
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| Description: | HISTAMINE H2 HRH2 RAT::P25102 |
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| Residue: | 358 |
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| Sequence: | MEPNGTVHSCCLDSMALKVTISVVLTTLILITIAGNVVVCLAVSLNRRLRSLTNCFIVSL
AATDLLLGLLVLPFSAIYQLSFTWSFGHVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEV
YGLVDGLVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMG
AFIICWFPYFTAFVYRGLRGDDAINEAVEGIVLWLGYANSALNPILYAALNRDFRTAYQQ
LFHCKFASHNSHKTSLRLNNSLLPRSQSREGRWQEEKPLKLQVWSGTELTHPQGNPIR
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| BDBM7966 |
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| n/a |
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| Name | BDBM7966 |
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| Synonyms: | 2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 | CHEMBL90 | Ceplene | Ergotidine | HISTAMINE DIHYDROCHLORIDE | Histamine | L-histamine | Peremin | [3H]histamine |
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| Type | Small organic molecule |
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| Emp. Form. | C5H9N3 |
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| Mol. Mass. | 111.1451 |
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| SMILES | NCCc1cnc[nH]1 |
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| Structure | 
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