| Reaction Details |
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 | Report a problem with these data |
| Target | Substance-K receptor |
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| Ligand | BDBM50071112 |
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| Substrate/Competitor | n/a |
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| Ki | 7.32±n/a nM |
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| Comments | PDSP_1755 |
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| Citation |  Kudlacz, EM; Shatzer, SA; Knippenberg, RW; Logan, DE; Poirot, M; van Giersbergen, PL; Burkholder, TP In vitro and in vivo characterization of MDL 105,212A, a nonpeptide NK-1/NK-2 tachykinin receptor antagonist. J Pharmacol Exp Ther277:840-51 (1996) [PubMed] |
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| More Info.: | Get all data from this article |
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| Substance-K receptor |
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| Name: | Substance-K receptor |
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| Synonyms: | NK2R_MESAU | Neurokinin 2 receptor | Neurokinin NK2 | TAC2R | TACR2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43436.75 |
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| Organism: | HAMSTER |
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| Description: | P51144 |
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| Residue: | 384 |
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| Sequence: | MGGRAIVTDTNIFSGLESNTTGVTAFSMPAWQLALWATAYLGLVLVAVTGNATVIWIILA
HERMRTVTNYFIINLALADLCMAAFNATFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
IYSMTAIAADRYMAIVHPFQPRLSAPITKATIAGIWLVALALASPQCFYSTITVDQGATK
CVVAWPNDNGGKMLLLYHLVVFVLVYFLPLVVMFVAYSVIGLTLWKRAVPRHQAHGANLR
HLHAKKKFVKAMVLVVLTFAICWLPYHLYFILGSFQKDIYYRKFIQQVYLALFWLAMSST
MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDRLELTRTPSLSRRVNRCHTKETLFMT
ADMTHSEATNGQVGSPQDVEPAAP
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| BDBM50071112 |
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| n/a |
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| Name | BDBM50071112 |
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| Synonyms: | CHEMBL56835 | N-[4-(4-Acetylamino-4-phenyl-piperidin-1-yl)-2-(3,4-dichloro-phenyl)-butyl]-N-methyl-benzamide | SR 48968 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H35Cl2N3O2 |
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| Mol. Mass. | 552.535 |
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| SMILES | CN(CC(CCN1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 |
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| Structure | 
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