| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2B |
|---|
| Ligand | BDBM28582 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 26.6±n/a nM |
|---|
| Comments | PDSP_719 |
|---|
| Citation |  Wainscott, DB; Lucaites, VL; Kursar, JD; Baez, M; Nelson, DL Pharmacologic characterization of the human 5-hydroxytryptamine2B receptor: evidence for species differences. J Pharmacol Exp Ther276:720-7 (1996) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| 5-hydroxytryptamine receptor 2B |
|---|
| Name: | 5-hydroxytryptamine receptor 2B |
|---|
| Synonyms: | 5-HT2B | 5-hydroxytryptamine receptor 2B | 5HT2B_RAT | Htr2b | Serotonin 2b (5-HT2b) receptor | Serotonin receptor 2a and 2b (5HT2A and 5HT2B) | Srl |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 53668.47 |
|---|
| Organism: | RAT |
|---|
| Description: | 5-HT2B HTR2B RAT::P30994 |
|---|
| Residue: | 479 |
|---|
| Sequence: | MASSYKMSEQSTISEHILQKTCDHLILTDRSGLKAESAAEEMKQTAENQGNTVHWAALLI
FAVIIPTIGGNILVILAVSLEKRLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEATW
PLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRTTAFVKITVVWL
ISIGIAIPVPIKGIEADVVNAHNITCELTKDRFGSFMLFGSLAAFFAPLTIMIVTYFLTI
HALRKKAYLVRNRPPQRLTRWTVSTVLQREDSSFSSPEKMVMLDGSHKDKILPNSTDETL
MRRMSSAGKKPAQTISNEQRASKVLGIVFLFFLLMWCPFFITNVTLALCDSCNQTTLKTL
LQIFVWVGYVSSGVNPLIYTLFNKTFREAFGRYITCNYQATKSVKVLRKCSSTLYFGNSM
VENSKFFTKHGIRNGINPAMYQSPVRLRSSTIQSSSIILLNTFLTENDGDKVEDQVSYI
|
|
|
|---|
| BDBM28582 |
|---|
| n/a |
|---|
| Name | BDBM28582 |
|---|
| Synonyms: | 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | CHEMBL6616 | DOI | DOI,(+) | DOI,(-) | [125I]2,5-dimethoxy-4-iodoamphetamine | [125I]4-iodo-2,5-dimethoxyphenylisopropylamine | [125I]DOI |
|---|
| Type | radiolabeled ligand |
|---|
| Emp. Form. | C11H16INO2 |
|---|
| Mol. Mass. | 321.1547 |
|---|
| SMILES | COc1cc(CC(C)N)c(OC)cc1I |
|---|
| Structure | 
|
|---|
Search and Browse
