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TargetGamma-aminobutyric acid receptor subunit alpha-6
LigandBDBM25878
Substrate/Competitorn/a
Ki>10000±n/a nM
CommentsPDSP_828
Citation Hadingham, KLGarrett, EMWafford, KABain, CHeavens, RPSirinathsinghji, DJWhiting, PJ Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors. Mol Pharmacol49:253-9 (1996) [PubMed]
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Gamma-aminobutyric acid receptor subunit alpha-6
Name:Gamma-aminobutyric acid receptor subunit alpha-6
Synonyms:GABA A alpha6 | GABA receptor alpha-6 subunit | GABRA6 | GBRA6_HUMAN
Type:Enzyme Catalytic Domain
Mol. Mass.:51029.60
Organism:Homo sapiens (Human)
Description:GABA A alpha6 0 HUMAN::Q16445
Residue:453
Sequence:
MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKT
DIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRN
GKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYP
KSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKM
GYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYA
TAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEI
VLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQY
SRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE
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  Blast E-value cutoff:
BDBM25878
n/a
NameBDBM25878
Synonyms:5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one | CHEMBL13280 | Flunitrazepam | [3H]Rohypnol | [3H]flunitrazepam
Typeradiolabeled ligand
Emp. Form.C16H12FN3O3
Mol. Mass.313.2832
SMILESCN1c2ccc(cc2C(=NCC1=O)c1ccccc1F)[N+]([O-])=O |c:9|
Structure
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