| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-glucosidase MAL12 |
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| Ligand | BDBM84972 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Ki | 9.4e+3± 4e+2 nM |
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| IC50 | 1.85e+4± 1.2e+3 nM |
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| Citation |  Kim JY; Lee JW; Kim YS; Lee Y; Ryu YB; Kim S; Ryu HW; Curtis-Long MJ; Lee KW; Lee WS; Park KH A novel competitive class of α-glucosidase inhibitors: (E)-1-phenyl-3-(4-styrylphenyl)urea derivatives. Chembiochem 11:2125-31 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-glucosidase MAL12 |
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| Name: | Alpha-glucosidase MAL12 |
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| Synonyms: | α-Glucosidase | Maltase | alpha-Glucosidase (α-Glucosidase) |
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| Type: | Protein |
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| Mol. Mass.: | 68084.32 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | P53341 |
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| Residue: | 584 |
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| Sequence: | MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCP
FYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFK
ESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASR
QVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHP
NWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSF
THVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADD
SPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSF
GKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQ
ESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNF
SGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
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| BDBM84972 |
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| n/a |
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| Name | BDBM84972 |
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| Synonyms: | Urea derivative, 16 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H16F2N2O2 |
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| Mol. Mass. | 366.3607 |
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| SMILES | Oc1ccc(\C=C\c2ccc(NC(=O)Nc3ccc(F)cc3F)cc2)cc1 |
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| Structure | 
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