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TargetHTR4
LigandBDBM50007892
Substrate/Competitorn/a
Ki 223.87±n/a nM
CommentsPDSP_621
Citation Ansanay HSebben MBockaert JDumuis A Pharmacological comparison between [3H]GR 113808 binding sites and functional 5-HT4 receptors in neurons. Eur J Pharmacol 298:165-74 (1996) [PubMed]  Article
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HTR4
Name:HTR4
Synonyms:5-HT-4 | 5-HT4 | 5-HT4L | 5-hydroxytryptamine receptor 4 | Serotonin 4 (5-HT4) receptor | Serotonin receptor 4
Type:Enzyme Catalytic Domain
Mol. Mass.:43970.99
Organism:MOUSE
Description:5-HT4 HTR4 MOUSE::P97288
Residue:388
Sequence:
MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSN
STWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRP
QPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRD
TVECGGQWESRCHLTATSPLVAAQPSDT
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  Blast E-value cutoff:
BDBM50007892
n/a
NameBDBM50007892
Synonyms:2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride | CHEMBL539261 | DAU 6215
TypeSmall organic molecule
Emp. Form.C16H20N4O2
Mol. Mass.300.3556
SMILESCN1C2CCC1CC(C2)NC(=O)n1c2ccccc2[nH]c1=O |TLB:9:7:1:3.4|
Structure
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