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TargetCholinergic, Nicotinic Alpha1Beta1DeltaGamma
LigandBDBM50049750
Substrate/Competitorn/a
Ki 384±n/a nM
CommentsPDSP_215
Citation Sullivan JPDonnelly-Roberts DBriggs CAAnderson DJGopalakrishnan MPiattoni-Kaplan MCampbell JEMcKenna DGMolinari EHettinger AMGarvey DSWasicak JTHolladay MWWilliams MArneric SP A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity alpha 4 beta 2 nicotinic acetylcholine receptor ligand. Neuropharmacology 35:725-34 (1996) [PubMed]  Article
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Cholinergic, Nicotinic Alpha1Beta1DeltaGamma
Name:Cholinergic, Nicotinic Alpha1Beta1DeltaGamma
Synonyms:Acetylcholine receptor subunit alpha
Type:Enzyme Catalytic Domain
Mol. Mass.:51863.95
Organism:RAT
Description:Cholinergic, Nicotinic Alpha1Beta1DeltaGamma 0 RAT::P25108
Residue:457
Sequence:
MELTAVLLLLGLCSAGTVLGSEHETRLVAKLFKDYSSVVRPVGDHREIVQVTVGLQLIQL
INVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDVVLYNNADGDF
AIVKFTKVLLDYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINP
ESDQPDLSNFMESGEWVIKEARGWKHWVFYSCCPNTPYLDITYHFVMQRLPLYFIVNVII
PCLLFSFLTSLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLF
TMVFVIASIIITVIVINTHHRSPSTHIMPEWVRKVFIDTIPNIMFFSTMKRPSRDKQEKR
IFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSAIEGVKYIAETMKSDQESNNASEEWK
YVAMVMDHILLGVFMLVCLIGTLAVFAGRLIELHQQG
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  Blast E-value cutoff:
BDBM50049750
n/a
NameBDBM50049750
Synonyms:(S)-3-(azetidin-2-ylmethoxy)pyridine | 3-((S)-1-Azetidin-2-ylmethoxy)-pyridine | A-159470 | A-85380 | CHEMBL59986
TypeSmall organic molecule
Emp. Form.C9H12N2O
Mol. Mass.164.2044
SMILESC(Oc1cccnc1)[C@@H]1CCN1 |r|
Structure
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