Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCholinergic, Nicotinic Alpha1Beta1DeltaGamma
LigandBDBM50004108
Substrate/Competitorn/a
Ki>10000±n/a nM
CommentsPDSP_1311
Citation Sullivan JPDonnelly-Roberts DBriggs CAAnderson DJGopalakrishnan MPiattoni-Kaplan MCampbell JEMcKenna DGMolinari EHettinger AMGarvey DSWasicak JTHolladay MWWilliams MArneric SP A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity alpha 4 beta 2 nicotinic acetylcholine receptor ligand. Neuropharmacology 35:725-34 (1996) [PubMed]  Article
More Info.:Get all data from this article
 
Cholinergic, Nicotinic Alpha1Beta1DeltaGamma
Name:Cholinergic, Nicotinic Alpha1Beta1DeltaGamma
Synonyms:Acetylcholine receptor subunit alpha
Type:Enzyme Catalytic Domain
Mol. Mass.:51863.95
Organism:RAT
Description:Cholinergic, Nicotinic Alpha1Beta1DeltaGamma 0 RAT::P25108
Residue:457
Sequence:
MELTAVLLLLGLCSAGTVLGSEHETRLVAKLFKDYSSVVRPVGDHREIVQVTVGLQLIQL
INVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDVVLYNNADGDF
AIVKFTKVLLDYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINP
ESDQPDLSNFMESGEWVIKEARGWKHWVFYSCCPNTPYLDITYHFVMQRLPLYFIVNVII
PCLLFSFLTSLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLF
TMVFVIASIIITVIVINTHHRSPSTHIMPEWVRKVFIDTIPNIMFFSTMKRPSRDKQEKR
IFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSAIEGVKYIAETMKSDQESNNASEEWK
YVAMVMDHILLGVFMLVCLIGTLAVFAGRLIELHQQG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50004108
n/a
NameBDBM50004108
Synonyms:(+-)-nicotine | (R,S)-nicotine | (RS)-nicotine | 3-(1-methylpyrrolidin-2-yl)pyridine | CHEMBL440464 | Nicotin | Nicotine-(+) | Nikotin | US8609708, 54 Nicotine | US9284322, Nicotine | nicotine
TypeSmall organic molecule
Emp. Form.C10H14N2
Mol. Mass.162.2316
SMILESCN1CCCC1c1cccnc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: