| Reaction Details |
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 | Report a problem with these data |
| Target | Hrh3 protein |
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| Ligand | BDBM22567 |
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| Substrate/Competitor | n/a |
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| Ki | 7943.28±n/a nM |
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| Comments | PDSP_1202 |
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| Citation |  Brown, JD; O'Shaughnessy, CT; Kilpatrick, GJ; Scopes, DI; Beswick, P; Clitherow, JW; Barnes, JC Characterisation of the specific binding of the histamine H3 receptor antagonist radioligand [3H]GR168320. Eur J Pharmacol311:305-10 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Hrh3 protein |
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| Name: | Hrh3 protein |
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| Synonyms: | HISTAMINE H3 | HRH3 | Hrh3 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37860.96 |
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| Organism: | RAT |
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| Description: | Q5PPG3 |
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| Residue: | 344 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRGSKPSASSASLEKRMKMVSQSITQRF
RLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDY
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| BDBM22567 |
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| n/a |
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| Name | BDBM22567 |
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| Synonyms: | 3H]pyrilamine | CHEMBL511 | Dorantamin | Mepyramine | N-(4-methoxybenzyl)-N ,N -dimethyl-N-pyridin-2-ylethane-1,2-diamine | N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine | PYRILAMINE | Pyranisamine | [3H]mepyramine | [3H]pyrilamine |
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| Type | radiolabeled ligand |
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| Emp. Form. | C17H23N3O |
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| Mol. Mass. | 285.384 |
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| SMILES | COc1ccc(CN(CCN(C)C)c2ccccn2)cc1 |
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| Structure | 
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