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TargetGamma-aminobutyric acid receptor subunit alpha-3
LigandBDBM50026756
Substrate/Competitorn/a
Ki 3460±n/a nM
CommentsPDSP_534
Citation Araujo, FTan, SRuano, DSchoemaker, HBenavides, JVitorica, J Molecular and pharmacological characterization of native cortical gamma-aminobutyric acidA receptors containing both alpha1 and alpha3 subunits. J Biol Chem271:27902-11 (1996) [PubMed]  Article
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Gamma-aminobutyric acid receptor subunit alpha-3
Name:Gamma-aminobutyric acid receptor subunit alpha-3
Synonyms:GABA A anti-Alpha3 | GABA A receptor alpha-3/beta-2/gamma-2 | GABA receptor alpha-3 subunit | GBRA3_RAT | Gabra-3 | Gabra3 | Gamma-aminobutyric acid receptor subunit alpha-3
Type:Enzyme Catalytic Domain
Mol. Mass.:55444.88
Organism:RAT
Description:GABA A Alpha3Beta2Gamma2 0 RAT::P20236
Residue:493
Sequence:
MITTQMWHFYVTRVGLLLLISILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS
TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ
TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL
YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTKAEVIYSWTLGKNKSVEVAQDGSRL
NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN
RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFMAVCYAFVFSALIEFATVN
YFTKRSWAWEGKKVPEALEMKKKTPAAPTKKTSTTFNIVGTTYPINLALDTEFSTISKAA
AAPSASSTPTVIASPKTTYVQDSPAETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYV
NRESAIKGMIRKQ
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  Blast E-value cutoff:
BDBM50026756
n/a
NameBDBM50026756
Synonyms:3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[4,3-b]pyridazine | CHEMBL13662 | CI-218872 | CL 218872 | CL218,872 | v3-Methyl-6-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[4,3-b]pyridazine
TypeSmall organic molecule
Emp. Form.C13H9F3N4
Mol. Mass.278.2326
SMILESCc1nnc2ccc(nn12)-c1cccc(c1)C(F)(F)F
Structure
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