| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-arrestin-1 |
|---|
| Ligand | BDBM22869 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 1000±n/a nM |
|---|
| Comments | PDSP_552 |
|---|
| Citation |  Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berl)124:57-73 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Beta-arrestin-1 |
|---|
| Name: | Beta-arrestin-1 |
|---|
| Synonyms: | ARRB1 | ARRB1_RABIT | Beta-arrestin-1 | Cholinergic, muscarinic | OPIATE Delta | PAF Platelet activating factor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 46360.54 |
|---|
| Organism: | RABBIT |
|---|
| Description: | Cholinergic, muscarinic 0 RABBIT::Q95223 |
|---|
| Residue: | 410 |
|---|
| Sequence: | MGDKGTRVFKKASPNGKLTVYLGKRGFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
PKLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
HPTAETTRLFLMSDKPLHLEASLDKEIYYHGEPIIVNVHVTNNTNKTVKKIKISVRQYAD
ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
ASSTLMREGANREILGIIVSYKVKVKLVVSRGGDVAVELPFTLMHPKPKEEPPHREVPEN
ETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEDDVTGSPRLNDR
|
|
|
|---|
| BDBM22869 |
|---|
| n/a |
|---|
| Name | BDBM22869 |
|---|
| Synonyms: | 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene | CLOZARIL | Clozapine | Leponex | US10259786, Clozapine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H19ClN4 |
|---|
| Mol. Mass. | 326.823 |
|---|
| SMILES | CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 |c:8,15| |
|---|
| Structure | 
|
|---|
Search and Browse
