Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGamma-aminobutyric acid receptor subunit alpha-4
LigandBDBM50017009
Substrate/Competitorn/a
Ki 8±n/a nM
CommentsPDSP_502
Citation Gunnersen, D; Kaufman, CM; Skolnick, P Pharmacological properties of recombinant "diazepam-insensitive" GABAA receptors. Neuropharmacology35:1307-14 (1996) [PubMed]  Article
More Info.:Get all data from this article
 
Gamma-aminobutyric acid receptor subunit alpha-4
Name:Gamma-aminobutyric acid receptor subunit alpha-4
Synonyms:GBRA4_RAT | Gabra4 | Gamma-aminobutyric acid receptor (GABA(A)) subunit alpha-4
Type:Enzyme
Mol. Mass.:60972.37
Organism:Rattus norvegicus (Rat)
Description:P28471
Residue:552
Sequence:
MVSVQKVPAIVLCSGVSLALLHVLCLATCLNESPGQNSKDEKLCPENFTRILDSLLDGYD
NRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLN
NMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFP
MDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSIT
GEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMT
TLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQMQKAKKKISKPPP
EVPAAPVLKEKHTETSLQNTHANLNMRKRTNALVHSESDVNSRTEVGNHSSKTTAAQESS
ETTPKAHLASSPNPFSRANAAETISAAARGLSSAASPSPHGTLQPAPLRSASARPAFGAR
LGRIKTTVNTTGVPGNVSATPPPSAPPPSGSGTSKIDKYARILFPVTFGAFNMVYWVVYL
SKDTMEKSESLM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50017009
n/a
NameBDBM50017009
Synonyms:2-Phenyl-2,3a-dihydro-pyrazolo[4,3-c]quinolin-3-one(CGS 8216) | 2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-3-one | 2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-3-one (CGS 8216) | 2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-3-one(CGS 8216) | 2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-3-one(CGS-8216) | 2-phenyl-2H-pyrazolo[4,3-c]quinolin-3(5H)-one | CGS 8216, 1 | CGS-8216 | CHEMBL19732
TypeSmall organic molecule
Emp. Form.C16H11N3O
Mol. Mass.261.278
SMILESO=c1n([nH]c2c1cnc1ccccc21)-c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: