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TargetGamma-aminobutyric acid receptor subunit alpha-6
LigandBDBM26263
Substrate/Competitorn/a
Ki 115±n/a nM
CommentsPDSP_1609
Citation Gunnersen, DKaufman, CMSkolnick, P Pharmacological properties of recombinant "diazepam-insensitive" GABAA receptors. Neuropharmacology35:1307-14 (1996) [PubMed]  Article
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Gamma-aminobutyric acid receptor subunit alpha-6
Name:Gamma-aminobutyric acid receptor subunit alpha-6
Synonyms:GABA A Alpha6Beta3Gamma2 | GABA A receptor alpha-6/beta-2/gamma-2 | GABA receptor alpha-6 subunit | GBRA6_RAT | Gabra-6 | Gabra6 | Gamma-aminobutyric acid receptor subunit alpha-6
Type:Enzyme Catalytic Domain
Mol. Mass.:51188.24
Organism:RAT
Description:GABA A Alpha6Beta2Gamma2 0 RAT::P30191
Residue:453
Sequence:
MLLLLPWLFSLLWIENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKT
DIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFKGPAEILSLNNLMVSKIWTPDTFFRN
GKKSIAHNMTTPNKLFRLMHNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYP
KSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKM
GYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYA
TAMDWFIAVCFAFVFSALIEFAAVNYFTNLQSQKAERQAQTAAKPPVAKSKTTESLEAEI
VVHSDSKYHLKKRISSLTLPIVPSSEASKVLSRTPILPSTPVTPPLLLPAIGGTSKIDQY
SRILFPVAFAGFNLVYWIVYLSKDTMEVSSTVE
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BDBM26263
n/a
NameBDBM26263
Synonyms:Anexate | CHEMBL407 | FLUMAZENIL | Ro15-1788 | Romazicon | [3H]Ro15-1788 | ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),3,5,10,12-pentaene-5-carboxylate
TypeSmall organic molecule
Emp. Form.C15H14FN3O3
Mol. Mass.303.2884
SMILESCCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(F)ccc-21
Structure
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