| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit alpha-6 |
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| Ligand | BDBM26267 |
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| Substrate/Competitor | n/a |
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| Ki | 5.3±n/a nM |
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| Comments | PDSP_1610 |
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| Citation |  Gunnersen, D; Kaufman, CM; Skolnick, P Pharmacological properties of recombinant "diazepam-insensitive" GABAA receptors. Neuropharmacology35:1307-14 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Gamma-aminobutyric acid receptor subunit alpha-6 |
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| Name: | Gamma-aminobutyric acid receptor subunit alpha-6 |
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| Synonyms: | GABA A Alpha6Beta3Gamma2 | GABA A receptor alpha-6/beta-2/gamma-2 | GABA receptor alpha-6 subunit | GBRA6_RAT | Gabra-6 | Gabra6 | Gamma-aminobutyric acid receptor subunit alpha-6 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51188.24 |
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| Organism: | RAT |
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| Description: | GABA A Alpha6Beta2Gamma2 0 RAT::P30191 |
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| Residue: | 453 |
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| Sequence: | MLLLLPWLFSLLWIENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKT
DIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFKGPAEILSLNNLMVSKIWTPDTFFRN
GKKSIAHNMTTPNKLFRLMHNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYP
KSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKM
GYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYA
TAMDWFIAVCFAFVFSALIEFAAVNYFTNLQSQKAERQAQTAAKPPVAKSKTTESLEAEI
VVHSDSKYHLKKRISSLTLPIVPSSEASKVLSRTPILPSTPVTPPLLLPAIGGTSKIDQY
SRILFPVAFAGFNLVYWIVYLSKDTMEVSSTVE
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| BDBM26267 |
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| n/a |
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| Name | BDBM26267 |
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| Synonyms: | RO-154513 | Ro15-4513 | [3H]Ro15-4513 | ethyl 12-azido-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate |
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| Type | radiolabeled ligand |
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| Emp. Form. | C15H14N6O3 |
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| Mol. Mass. | 326.3101 |
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| SMILES | CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(ccc-21)N=[N+]=[N-] |
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| Structure | 
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