| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 6 |
|---|
| Ligand | BDBM50004051 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 900±n/a nM |
|---|
| Comments | PDSP_2029 |
|---|
| Citation |  Conn, PJ; Pin, JP Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharmacol Toxicol37:205-37 (1997) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Metabotropic glutamate receptor 6 |
|---|
| Name: | Metabotropic glutamate receptor 6 |
|---|
| Synonyms: | GPRC1F | GRM6 | GRM6_HUMAN | MGLUR6 | Metabotropic glutamate receptor 6 | glutamate receptor, metabotropic 6 precursor | metabotropic glutamate 6 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 95479.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | metabotropic glutamate 6 GRM6 HUMAN::O15303 |
|---|
| Residue: | 877 |
|---|
| Sequence: | MARPRRAREPLLVALLPLAWLAQAGLARAAGSVRLAGGLTLGGLFPVHARGAAGRACGQL
KKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGR
GDGDEVGVRCPGGVPPLRPAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPE
LSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREA
GGVCIAQSIKIPREPKPGEFSKVIRRLMETPNARGIIIFANEDDIRRVLEAARQANLTGH
FLWVGSDSWGAKTSPILSLEDVAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEF
WEENFNCKLTSSGTQSDDSTRKCTGEERIGRDSTYEQEGKVQFVIDAVYAIAHALHSMHQ
ALCPGHTGLCPAMEPTDGRMLLQYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNG
SASSGGYQAVGQWAETLRLDVEALQWSGDPHEVPSSLCSLPCGPGERKKMVKGVPCCWHC
EACDGYRFQVDEFTCEACPGDMRPTPNHTGCRPTPVVRLSWSSPWAAPPLLLAVLGIVAT
TTVVATFVRYNNTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPGAAVCAARRLFLGLG
TTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFSLTSLQVVGMIAWLGARP
PHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFN
EAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKT
YVILFHPEQNVQKRKRSLKATSTVAAPPKGEDAEAHK
|
|
|
|---|
| BDBM50004051 |
|---|
| n/a |
|---|
| Name | BDBM50004051 |
|---|
| Synonyms: | 2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosphono-butyric acid (AP4) | 4-Amino Phosphonobutyrate | CHEMBL285843 | GlcN-6-P synthase inhibitor, 1 (racemic mixture) | L-AP4 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C4H10NO5P |
|---|
| Mol. Mass. | 183.0997 |
|---|
| SMILES | NC(CCP(O)(O)=O)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
