| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM85079 |
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| Substrate/Competitor | n/a |
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| Ki | 240±n/a nM |
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| Comments | PDSP_2284 |
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| Citation |  Mos, J; Van Hest, A; Van Drimmelen, M; Herremans, AH; Olivier, B The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. Eur J Pharmacol325:145-53 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT2A | HTR2A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 105583.25 |
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| Organism: | pigeon |
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| Description: | 5-HT2A HTR2A pigeon::A0A1V4J4E5 |
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| Residue: | 946 |
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| Sequence: | MGVFVKDSSDSAYLTPERKLALGRGKAQGKSRQAAYLSEEKNKPRSTGTGFTQVCSLEVK
KLFQIPPFWRRLKKRDAKLAKHNEEYSESVQSEPNRILRVGSDVQPGFSMYAYTGLPMEL
KTKHFSIQSNSVSNFAMDILCDQESSVNPTAKSLIQINHERRLYRNVYGAGEINASHLFN
LTVDSENLTNVSSESSVTPPCYSSLFQLSQKNWPALLTVIVIVLTIAGNILVIMAVSLEK
KLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYAWPLPRKLCAIWIYLDVLFSTASI
MHLCAISLDRYIAIRNPIHHSRFNSRTKAFAKIIAVWTISVGISMPVPVFGLQDDSKVFK
KDSCLLADDNFVLVGSFVAFFIPLTIMVVTYFLTIKSLQKEAMLCVNDIGPKTKFASFSF
LPQSSLSSEKLFQRSLNRDVGTSGRRTMQSISNEQKASKVLGIVFFLFVVMWCPFFITNV
MAVICKESCNQEVIGELLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCRYKEEKK
PFQLILVNTIPALAYNSSQLQLAQMKSLKKEAKMMAKDYSMVTIGIHHLDGTSKGSISPV
NENVSETAAQHPPWQTQTGRLRALPRSAGGPGRQAGRLEAAPARGQPPPPVLRRAAPPLL
LVKAMALKQVSSNKCFEGFQKVFEHDSAELKCKMKFGIYLPPKAETGKCPVLYWLSGLTC
TEQNFITKAGFHQAAAEHGLIVVAPDTSPRGCNIEGEDESWDFGTGAGFYVDATEDPWKT
NYRMYSYIKDELPKLINANFPTDPERMSIFGHSMGGHGALILALKNPGKYKSVSAFAPIC
NPMQCQWGKKALGGYLGSDASKWEAYDATQLVKSYPDSHLDILIDQGKDDQFLSAGQLLP
DNFIAACTERKIPVVFRLQQGYDHSYFFIATFINDHIKHHAKYLNA
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| BDBM85079 |
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| n/a |
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| Name | BDBM85079 |
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| Synonyms: | 2-[4-[4-[(7-Chloro-2,3-dihydro-1,4-benzodioxin)-5-yl]-1-piperazinyl]butyl]-1,2-benzisothiazol-3(2H)-one 1,1-dioxide | CHEMBL79261 | DU-125530 | DU125530 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26ClN3O5S |
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| Mol. Mass. | 491.988 |
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| SMILES | Clc1cc2OCCOc2c(c1)N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 |
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| Structure | 
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