| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
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| Ligand | BDBM85097 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_1670 |
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| Citation |  Kennett, GA; Wood, MD; Bright, F; Trail, B; Riley, G; Holland, V; Avenell, KY; Stean, T; Upton, N; Bromidge, S; Forbes, IT; Brown, AM; Middlemiss, DN; Blackburn, TP SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. Neuropharmacology36:609-20 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Alpha-1B adrenergic receptor |
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| Name: | Alpha-1B adrenergic receptor |
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| Synonyms: | ADA1B_MESAU | ADRA1B | Adrenergic receptor alpha | Alpha-1b adrenergic receptor | adrenergic Alpha1B |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 56514.13 |
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| Organism: | C.H.O. |
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| Description: | adrenergic Alpha1B ADRA1B C.H.O.::P18841 |
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| Residue: | 515 |
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| Sequence: | MNPDLDTGHNTSAPAQWGELKDANFTGPNQTSSNSTLPQLDVTRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSATLEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFM
RILGCQCRSGRRRRRRRRLGACAYTYRPWTRGGSLERSQSRKDSLDDSGSCMSGSQRTLP
SASPSPGYLGRGAQPPLELCAYPEWKSGALLSLPEPPGRRGRLDSGPLFTFKLLGEPESP
GTEGDASNGGCDATTDLANGQPGFKSNMPLAPGHF
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| BDBM85097 |
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| n/a |
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| Name | BDBM85097 |
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| Synonyms: | CAS_181632-25-7 | CHEMBL14563 | SB 242084 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19ClN4O2 |
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| Mol. Mass. | 394.854 |
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| SMILES | Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1Cl |
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| Structure | 
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