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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 2A | ||
| Ligand | BDBM30704 | ||
| Substrate/Competitor | n/a | ||
| Ki | 0.18±n/a nM | ||
| Comments | PDSP_1209 | ||
| Citation |  Bonhaus, DW; Weinhardt, KK; Taylor, M; DeSouza, A; McNeeley, PM; Szczepanski, K; Fontana, DJ; Trinh, J; Rocha, CL; Dawson, MW; Flippin, LA; Eglen, RM RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist. Neuropharmacology36:621-9 (1997) [PubMed] Article | ||
| More Info.: | Get all data from this article | ||
| 5-hydroxytryptamine receptor 2A | |||
| Name: | 5-hydroxytryptamine receptor 2A | ||
| Synonyms: | 5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 52852.05 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | Rat cortex membranes 5-HT2A receptors. | ||
| Residue: | 471 | ||
| Sequence: |
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| BDBM30704 | |||
| n/a | |||
| Name | BDBM30704 | ||
| Synonyms: | (phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamate | CHEMBL19215 | METERGOLINE | MLS000069437 | N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamic acid (phenylmethyl) ester | N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamic acid benzyl ester | SMR000059050 | benzyl N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamate | cid_28693 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H29N3O2 | ||
| Mol. Mass. | 403.5167 | ||
| SMILES | CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1cn(C)c3cccc2c13 | ||
| Structure | 
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