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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 2B | ||
| Ligand | BDBM50024204 | ||
| Substrate/Competitor | n/a | ||
| Ki | 1.44±n/a nM | ||
| Comments | PDSP_1206 | ||
| Citation |  Bonhaus, DW; Weinhardt, KK; Taylor, M; DeSouza, A; McNeeley, PM; Szczepanski, K; Fontana, DJ; Trinh, J; Rocha, CL; Dawson, MW; Flippin, LA; Eglen, RM RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist. Neuropharmacology36:621-9 (1997) [PubMed] Article | ||
| More Info.: | Get all data from this article | ||
| 5-hydroxytryptamine receptor 2B | |||
| Name: | 5-hydroxytryptamine receptor 2B | ||
| Synonyms: | 5-HT-2B | 5-HT2B | 5-hydroxytryptamine (serotonin) receptor 2B [Homo sapiens] | 5-hydroxytryptamine receptor 2B (5-HT2B) | 5-hydroxytryptamine receptor 2C (5HT2C) | 5HT2B_HUMAN | HTR2B | Serotonin (5-HT3) receptor | Serotonin 2b (5-HT2b) receptor | Serotonin Receptor 2B | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 54312.47 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Receptor binding assays were performed using human clone stably expressed in CHO cells. | ||
| Residue: | 481 | ||
| Sequence: |
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| BDBM50024204 | |||
| n/a | |||
| Name | BDBM50024204 | ||
| Synonyms: | 1H-imidazo[4,5-c]pyridine derivative | 2N-[4,7-dimethyl-(6aR,9S,10aR)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]-2-dimethylaminosulfonamide | 4,7-dimethyl-(6aR,9S,10aR)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-amino-N,N-dimethyl sulfonamide | 4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-amine-sulfonamide | 9-N,N-dimethylsulfamide-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline | CHEMBL12314 | ChEMBL_10959 | MESULERGINE | N'-4,7-Dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-N'-,N'-dimethyl-sulphonediamine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H26N4O2S | ||
| Mol. Mass. | 362.49 | ||
| SMILES | CN(C)S(=O)(=O)N[C@H]1C[C@H]2[C@@H](Cc3cn(C)c4cccc2c34)N(C)C1 | ||
| Structure | 
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