| Reaction Details |
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 | Report a problem with these data |
| Target | Homoserine kinase |
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| Ligand | BDBM85125 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Inhibition Assay |
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| pH | 7.5±0 |
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| Temperature | 310.15±0 K |
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| Ki | 3.58e+4± 2.7e+3 nM |
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| Citation |  De Pascale, G; Griffiths, EJ; Shakya, T; Nazi, I; Wright, GD Identification and characterization of new inhibitors of fungal homoserine kinase. Chembiochem12:1179-82 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Homoserine kinase |
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| Name: | Homoserine kinase |
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| Synonyms: | KHSE_ECOLI | thrB |
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| Type: | Enzyme |
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| Mol. Mass.: | 33619.26 |
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| Organism: | Escherichia coli |
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| Description: | P00547 |
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| Residue: | 310 |
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| Sequence: | MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEP
RENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLND
TRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGI
KVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLP
GFRQARQAVAEIGAVASGISGSGPTLFALCDKPETAQRVADWLGKNYLQNQEGFVHICRL
DTAGARVLEN
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| BDBM85125 |
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| n/a |
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| Name | BDBM85125 |
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| Synonyms: | Thr1 inhibitor, 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19NO2S |
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| Mol. Mass. | 277.382 |
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| SMILES | CC(C)Cc1nc2sc3CCCCCc3c2c(=O)o1 |
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| Structure | 
|
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