| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
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| Ligand | BDBM85135 |
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| Substrate/Competitor | n/a |
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| Ki | 1.25±n/a nM |
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| Comments | PDSP_1622 |
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| Citation |  Bonhaus, DW; Berger, J; Adham, N; Branchek, TA; Hsu, SA; Loury, DN; Leung, E; Wong, EH; Clark, RD; Eglen, RM [3H]RS 57639, a high affinity, selective 5-HT4 receptor partial agonist, specifically labels guinea-pig striatal and rat cloned (5-HT4S and 5-HT4L) receptors. Neuropharmacology36:671-9 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 4 |
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| Name: | 5-hydroxytryptamine receptor 4 |
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| Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46117.31 |
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| Organism: | RAT |
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| Description: | 5-HT4 HTR4 RAT::Q62758 |
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| Residue: | 406 |
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| Sequence: | MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSN
STFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRP
QTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRD
TVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS
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| BDBM85135 |
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| n/a |
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| Name | BDBM85135 |
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| Synonyms: | RS 57639 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H29ClN2O5 |
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| Mol. Mass. | 460.95 |
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| SMILES | COc1cc(N)c(Cl)cc1C(=O)OCC1CCN(CCc2ccc3OCCOc3c2)CC1 |
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| Structure | 
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