Reaction Details |
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Target | Prostaglandin E2 receptor EP2 subtype |
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Ligand | BDBM50101828 |
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Substrate/Competitor | n/a |
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Ki | 10±n/a nM |
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Comments | PDSP_1459 |
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Citation | Kiriyama, M; Ushikubi, F; Kobayashi, T; Hirata, M; Sugimoto, Y; Narumiya, S Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol122:217-24 (1997) [PubMed] Article |
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More Info.: | Get all data from this article |
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Prostaglandin E2 receptor EP2 subtype |
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Name: | Prostaglandin E2 receptor EP2 subtype |
Synonyms: | PE2R2_MOUSE | PGE receptor, EP2 subtype | Prostaglandin E2 | Prostaglandin E2 receptor EP2 subtype | Prostanoid EP2 receptor | Ptger2 | Ptgerep2 |
Type: | G-protein coupled receptor |
Mol. Mass.: | 40495.26 |
Organism: | Mus musculus (Mouse) |
Description: | n/a |
Residue: | 362 |
Sequence: | MDNFLNDSKLMEDCKSRQWLLSGESPAISSVMFSAGVLGNLIALALLARRWRGDTGCSAG
SRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESHACTYFAFTMTFF
SLATMLMLFAMALERYLSIGYPYFYRRHLSRRGGLAVLPVIYGASLLFCSLPLLNYGEYV
QYCPGTWCFIRHGRTAYLQLYATMLLLLIVAVLACNISVILNLIRMHRRSRRSRCGLSGS
SLRGPGSRRRGERTSMAEETDHLILLAIMTITFAICSLPFTIFAYMDETSSLKEKWDLRA
LRFLSVNSIIDPWVFAILRPPVLRLMRSVLCCRTSLRTQEAQQTSCSTQSSASKQTDLCG
QL
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BDBM50101828 |
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n/a |
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Name | BDBM50101828 |
Synonyms: | 7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-oct-1-enyl)-5-oxo-cyclopentyl]-heptanoic acid | CHEMBL62570 | PGE1 | US9180116, PGE1 |
Type | Small organic molecule |
Emp. Form. | C20H34O5 |
Mol. Mass. | 354.481 |
SMILES | CCCCC[C@@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O |
Structure |
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